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In our Drug Discovery division, we offer a range of services to accelerate the process of identifying and optimizing potential drug candidates. Our extensive Chemical Library provides a valuable resource for screening and identifying promising leads. With our state-of-the-art facilities and advanced techniques, we perform rigorous Lead Identification and Characterization studies to assess the efficacy and safety profiles of potential candidates. Through our collaborative approach, we work closely with clients to optimize leads through Lead Optimization strategies, ensuring the development of high-quality drug candidates.
In our Pre-Clinical division, we provide comprehensive services to support the early stages of drug development. Our experienced team focuses on key aspects such as Process Development, ensuring that the manufacturing processes are optimized and scalable for further development. We also excel in Analytical Method Development, designing and validating robust methods to accurately assess the quality and characteristics of the drug candidate.
For toxicology studies, we offer Gram scale synthesis capabilities, producing sufficient quantities of the compound to support rigorous testing and evaluation. Additionally, our expertise in Impurity Identification and Characterization allows for a thorough understanding of potential impurities and their impact on the drug candidate.
To support regulatory submissions, we conduct Physicochemical Property studies that provide crucial data on the compound’s solubility, stability, and other key properties. These studies contribute to the development of the Investigational Medicinal Product Dossier (IMPD).
Stability studies are integral to our pre-clinical services, ensuring that the drug candidate remains stable under various storage conditions. This data is crucial for determining shelf life and storage recommendations.
Furthermore, our Pre-formulation and Formulation Development services aim to optimize the drug candidate’s formulation, enhancing its delivery, bioavailability, and stability.
Overall, our Pre-Clinical services offer a comprehensive suite of capabilities to support the early stages of drug development, helping our clients make informed decisions and progress towards successful clinical trials.
Our Chemistry Capabilities encompass a wide range of versatile and advanced chemistry techniques. We excel in cryogenic reactions, including p-lithium, methyl lithium, and Grignard reactions, conducted at extremely low temperatures. Our expertise extends to heterocyclic chemistry, enabling us to handle diverse heterocyclic compounds. Additionally, we specialize in hydrogenation reactions, with the ability to handle pressures of up to 20 bar.
Our capabilities also include Argon metallic reactions across a wide range of conditions, as well as metal mediator reactions utilizing precious metals like palladium, rhodium, and others. We are proficient in forming C-C-C-N and C-S bonds. Furthermore, we employ innovative approaches to obtain nanoparticles such as nanopalladium, nanocopper, and nanonickel, which find applications in various areas of chemistry.
Boronic and phosphorite chemistry is another area of our expertise, along with asymmetric synthesis of lipids, carbohydrates, and compounds involving azide, sulfur, and sodium cyanide. We are skilled in working with amidates, phosphoramidates, nucleotides, and nucleosides. Our commitment to sustainable process development drives us to explore fast-track development approaches and incorporate greener methodologies such as biotransformation and continuous flow reactions.
At the core of our company’s philosophy is embracing new technologies and innovative thinking. We strive to apply out-of-the-box solutions to existing challenges, ensuring we remain at the forefront of scientific advancements. In line with this, we are well-positioned to support antibody drug conjugation and oligotherapeutics programs. Whether it’s early-stage chemistries, toxins, linkers, lipid nanoparticles, or galanac-based compounds, we possess the knowledge and experience to contribute to these cutting-edge areas.
These chemistry capabilities and hands-on experiences are at the heart of the services we provide. By leveraging our expertise and staying abreast of the latest advancements, we are dedicated to delivering innovative and effective solutions to meet our clients’ needs.
Our R&D center boasts a spacious area of 20,000 square feet, providing ample room for conducting our research and development activities. With 45 fume hoods and a team of 60 chemists, including analytical experts, we have the capacity to carry out diverse projects simultaneously. The ratio of Ph.D. holders to M.Sc. graduates is 1:5, ensuring a strong blend of advanced expertise and practical knowledge.
Our center is fully equipped with state-of-the-art analytical instruments, which are essential for method development and release testing. We have a dedicated development laboratory equipped with stability chambers, allowing us to conduct stability studies and evaluate the performance of our formulations at an early stage. Additionally, our quality control labs also feature stability chambers, enabling us to ensure the quality and stability of our products throughout their lifecycle.
One of our core competencies lies in fast track process development and seamless technology transfer. Our experienced team specializes in efficiently transferring processes from one site to another. Moreover, we prioritize rapid stability verification, allowing us to quickly assess the stability of our products and make informed decisions during the development phase.
These capabilities serve as key differentiators, setting us apart from others in the industry. By leveraging our strengths in process development, technology transfer, and rapid stability verification, we ensure that our products meet the highest standards of quality, time-efficiency, and stability.
Our company possesses several core competencies that set us apart in the industry and enable us to deliver exceptional results for our clients. These competencies include:
These core competencies reflect our commitment to excellence, innovation, and delivering high-quality pharmaceutical products and services to our clients.
At Teadus Pharma, our goal is to provide our clients with exceptional technical expertise, grounded in our specialist chemistry knowledge and robust project management capabilities. We are committed to delivering excellence, guided by internationally recognized ethical and quality standards.
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